Rutinib tablet 5mg and 10mg (Ruxolitinib)

Composition: Each tablet contains Ruxolitinib 10mg as Ruxolitinib Phosphate INN.
Indications: Myelofibrosis: It is indicated for treatment of patients with intermediate or high-risk myelofibrosis (MF), including primary MF, post-polycythemia vera MF and post-essential thrombocythemia MF.
Polycythemia Vera: Ruxolitinib is indicated for treatment of patients with polycythemia vera (PV) who have had an inadequate response to or are intolerant of hydroxyurea.
Dosage and Administration: Myelofibrosis: The recommended starting dose of Ruxolitinib is based on platelet count.
Ruxolitinib Starting Doses for MyelofibrosisPlatelet CountStarting DoseGreater than 200 X 109/L20 mg orally twice daily100 X 109/L to 200 X 109/L15 mg orally twice daily50 X 109/L to less than 100 X 109/L5 mg orally twice dailyPolycythemia Vera: The recommended starting dose of Ruxolitinib is 10 mg twice daily. Doses may be titrated based on safety and efficacy. Or as directed by the registered physician.Use in Pregnancy and Lactation: There are no adequate and well-controlled studies in pregnant women. Nursing mother: It is not known whether Ruxolitinib is excreted in human milk. Because many drugs are excreted in human milk, breastfeeding should be discontinued during treatment with Ruxolitinib and for two weeks after the final dose.Packing: Each box contains 30’s tablets in a Container.